The enzymes could now potentially be used to sustainably convert wood biomass into valuable chemical commodities such as biofuels.
As an alternative to coal and oil, wood is increasingly one of the more promising sources of advanced biofuels . However, despite its potential, it is a difficult material to breakdown.
Current wood biorefineries have to use pre-treatment processes, making the conversion of wood into fuels and products expensive and energy-consuming.
In ecosystems fungi play a significant role in breaking down wood within the carbon cycle, releasing nutrients back into soil. This property of fungi inspired the researchers to investigate the mechanisms that allow this process to take place.
Co-author of the paper, Professor Paul Walton from the Department of Chemistry at the University of York said: “Back in 2010 we made the key discovery that a group of enzymes found in fungi, contain copper – these enzymes are now known to be an important component in the decomposition of biomass by biology. This research builds on that work by identifying further enzymes from this class which have the ability to break down wood’s challenging molecular structure.”
The research, reported in Nature Chemical Biology, has shown that the family of enzymes, called lytic polysaccharide monooxygenases (LPMOs), are capable of breaking down xylans – carbohydrate molecules commonly found in wood biomass that are particularly resistant to degradation.
Working in collaboration with French researchers from the Le Centre National de la Recherche Scientifique (CNRS) Marseille, the researchers isolated the enzymes from fungi that play a vital role in the terrestrial carbon cycle and dominate wood decomposition in forests.
Co-author of the paper Gideon Davies from the Department of Chemistry at the University of York said: “The findings advance our knowledge of the way in which woody biomass degrades in nature.”
This research was carried out by Professor Paul Walton and Professor Gideon Davies from the Department of Chemistry. The study was funded by the European Commission, the UK Biotechnology and Biological Sciences Research Council (BBSRC) the Centre National de la Recherche Scientifique (CNRS) and the French Infrastructure for Integrated Structural Biology (FRISBI).
Lytic xylan oxidases from wood-decay fungi unlock biomass degradation is published in Nature Chemical Biology.
Photo: The role fungi plays in breaking down wood within the carbon cycle inspired researchers to investigate the mechanisms that allow this process to take place.
